Dietary indole compounds found in broccoli, cabbage, and other cruciferous vegetables exert a strong protective effect on tissues such as breast, cervix, and prostate that are most susceptible to the effects of undesirable estrogen metabolites, such as 16-alpha hydroxy-estrone. Indole compounds favorably influence steroid hormone metabolism and help rebalance estrogen in favor of 2-hydroxyestrone, a protective estrogen metabolite. Dietary indoles also stimulate liver detoxification enzymes, inhibit DNA damage, and regulate cell cycle progression. Indole-3-carbinol (I3C), the most prominent dietary indole, readily breaks down in the presence of stomach acid into diindolylmethane (DIM) and other associated indole compounds that are subsequently absorbed. Although diindolylmethane has been claimed to be the preferred form for dietary supplementation, we find the available published evidence does not adequately support this conclusion. The bulk of scientific data reports benefits from taking I3C. Data in direct support of taking DIM alone is suggestive but still inconclusive. Rather, it appears that the total content of dietary indoles is most relevant. Indole Forté contains I3C, DIM, and other indoles for more complete protection. Increased indole intake may be especially important for women or men with estrogen-dominant health conditions.
Suggested Adult Use: 1 to 2 capsules daily with food.
Free of: Klaire Labs® brands of products are free of artificial flavors, preservatives, and colorings. Naturally-derived, inert excipient materials, including cellulose-based excipients, vegetable-derived magnesium stearate, L-leucine, and silicon dioxide are used in very small amounts as tableting and encapsulation aids. Tableted products are protected with an inert, water-soluble cellulose coating that dissolves readily upon ingestion, thus facilitating tablet disintegration time. Vegetarian capsules made of plant cellulose are used exclusively for two-piece encapsulated products. Common allergens such as wheat, corn, soy, yeast, and dairy are avoided unless otherwise specified on the label.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.